Thrombotic Microangiopathy due to Malignant Hypertension Following Corticosteroid Therapy for Microscopic Polyangitis

Thrombotic microangiopathy due to malignant hypertension following corticosteroid therapy for microscopic polyangitis.

A 78-year-old woman was treated with 40 mg of prednisolone for microscopic polyangitis, and favorable effects were observed. However, her blood pressure increased and she developed severe thrombocytopenia. Thrombotic microangiopathy (TMA) due to malignant hypertension was suspected and she was treated with an angiotensin-converting enzyme inhibitor; her platelet count then rose. She showed a cl...

The malignant hypertension-thrombotic microangiopathy link.

Acute renal failure secondary to malignant hypertension induced thrombotic microangiopathy.

T thrombotic microangiopathy (TMA) represents a discreet group of disorders with common pathological features including fibrinoid necrosis, endothelial cell injury, and obstruction of vessels.1 The clinical presentation of TMA includes microangiopathic hemolytic anemia, thrombocytopenia, and functional impairment of various organ systems. Hemolytic uremic syndrome (HUS) and thrombotic thrombocy...

A case of lipoprotein glomerulopathy with thrombotic microangiopathy due to malignant hypertension

BACKGROUND Lipoprotein glomerulopathy (LPG) is a rare inherited renal disease characterized by intraglomerular lipoprotein within the lumina of severely dilated glomerular capillaries. The common clinical presentation of LPG includes proteinuria or nephrotic syndrome. Hypertension and anemia were thought to be mild in LPG. Thrombotic microangiopathy (TMA) in LPG has not been previously reported...

Pulmonary tumour thrombotic microangiopathy: unclassifiable pulmonary hypertension?

References 1 Simonneau G, Gatzoulis MA, Adatia I, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2013; 62: D34–D41. 2 Gurtner HP. Aminorex and pulmonary hypertension. A review. Cor Vasa 1985; 27: 160–171. 3 Kay JM, Smith P, Heath D. Aminorex and the pulmonary circulation. Thorax 1971; 26: 262–270. 4 Simonneau G, Fartoukh M, Sitbon O, et al. Primary pulmonary...